关键词: 生长肥育猪, 铜, 铜残留, 病理变化

Abstract: The effect of copper supplementation on the copper content and histopathological changes of the body tissues in the growing-finishing pigs is investigated in this study. In the experiment, sixty Duroc×Landrance×Yorkshire(DLY) piglets averaging 20kg were assigned to five dietary copper content treatment in a single factorial arrangement during 20~100 kg stage. Pigs received a diet containing about 0, 100, 200, 300, 400 mgCu/kg diet, respectively. The pigs were slaughtered when they weighted 100 kg. The results show that the copper content in the body tissues tends to increase with the increase of the copper supplementation. The regression equations of the copper contents in the liver(y₁, mg/kg) and the kidney(y₂, mg/kg) with the copper supplementation(x, mg/kg) are:y₁=11.3963-0.2920x+0.0022x²(R²=0.814, P=0.036) and y₂=8.7583-0.0043x+0.0002x²(R²=0.975, P=0.025). According to the regression equations, if "y₁" and "y₂" do not exceed 10 mg/kg, "x" can not exceed 127.76 mg/kg and 90.27 mg/kg. At histopathological level, the hepatocytes, epithelial cells of renal tubule, spleen and cardiac muscle cells mainly show granular and vacuolar degeneration. Supplemented with 100~400 mgCu/kg diet does harm to the body tissues at different extent.

Key words: growing-fishing pigs, copper, copper content, histopathological changes