关键词: 喹乙醇, 凋亡, 电子显微观察, 鲤鱼

Abstract: The test was conducted with 60 fish for 30 days, with dose of 200mg olaquindox/kg feed. 4 fish was killed each time to observe the apoptosis of the hepatic cells by electron microscope on the 7 d, 14 d, 20 d, 25 d, 30 d individually after poisoning. The results show that olaquindox can induce the apoptosis of the hepatic cell of common carp (Cyprinus carpio). The characteristic of apoptosis hepatic cells shows Chromatin condensation, margination, half-moon and then cracking, moving blow the nuclear membrane; Apoptosis bodies appearing in hepatic cells. Furthermore, the apoptosis percentage of hepatic cell increases with the test time last.

Key words: olaquindox, apoptosis, electron microscope, Cyprinus carpio