关键词: 小鹅瘟, 病理形态学, 超微结构, 病理学[47KC], 禽病[49NB]

Abstract: 40 five-day-old goslings were experimentaly infected with gosling plague virus by oral administration. The infected goslings were killed at distinct postinfection stages. The first changes were found in the small intestine. The epithelial cells at the villus tip fell off in the first day postinf-ection. Then necrosis and falling went down to the bases of the villus. Meanwhile, the necrosis and infiltration with the inflammatory cells occurred in the membrana propria. Along with those changes aggravating, the fibrinous necrotic enteritis showed in the small intestine, especially, the middle-lower sections of the small intestine. As a result, a particular coagulative embolus took shape, and blocked up the intestinal cavity. Parenchymatous organs appeared degeneration and infiltration with the inflammatory cells. Liver, spleen, pancreas, thymus, bursa of Fabricius necrosed focally. Observing through electron microscope, the virus first damaged the epithelia cells at the villus tip of the small intes-tines. The mitochondria in the cells of the hear and liver swelled. The crestbecam short or disappeared, and ground substance empty. Also, endoplasmic reticulum dilated.

Key words: GOSILING PLAGUE, PATHOMORPHOLOGIAL, ULTRASTRUCTURE, PATHOLOGY, POULTRY DISEASES