四川农业大学学报 ›› 2013, Vol. 31 ›› Issue (01): 83-86.doi: 10.3969/j.issn.1000-2650.2013.01.016

• 研究论文 • 上一篇    下一篇

牛蛙(Rana catesbeiana)腐皮红腿症病理学观察

黄小丽1, 邓永强2, 刘艳丽1, 汪开毓3, 耿毅3, 杜宗君1   

  1. 1. 四川农业大学动物科技学院, 四川 雅安 625014;
    2. 四川省动物疫病预防控制中心, 成都 610041;
    3. 四川农业大学动物医学院, 四川 雅安 625014
  • 收稿日期:2012-10-09 出版日期:2013-03-31 发布日期:2017-02-28
  • 作者简介:黄小丽,博士,主要从事水产病害研究,E-mail:hxldyq@126.com。
  • 基金资助:
    四川省教育厅青年基金项目(09ZB055)

Pathological Changes of Rana catesbeiana with Rotten-skin and Red-leg Disease

HUANG Xiao-li1, DENG Yong-qiang2, LIU Yan-li1, WANG Kai-yu3, GENG Yi3, DU Zong-jun1   

  1. 1. College of Animal Science and Technology, Sichuan Agricultural University, Yaan 625014, Sichuan, China;
    2. Sichuan Provincial center for Animal Disease Prevention and Control, Chengdu 610041, China;
    3. College of Veterinary Medicine, Sichuan Agricultural University, Yaan 625014, Sichuan, China
  • Received:2012-10-09 Online:2013-03-31 Published:2017-02-28

摘要: [目的] 观察牛蛙腐皮红腿症的病理学改变。[方法] 通过石蜡切片,H·E染色法,对发生腐皮红腿症的牛蛙自然病例进行病理形态学变化观察。[结果] 剖检发现病蛙头、背部皮肤腐烂,露出肌肉,腹部及腿部皮肤出血发红;肝肿大,严重充出血,呈花瓣状;脾、肾出血肿大,颜色加深;胃肠道黏膜出血发红,内充满大量淡黄色黏液。镜检以全身多组织器官充出血、实质细胞变性、坏死及炎症细胞浸润为主要特征,以皮肤肌肉、肝、脾、肾和胃肠道的变化最为明显。胃肠道表现为严重的出血性、卡他性炎症,胃肠黏膜上皮严重坏死、脱落;肝细胞严重空泡变性,并出现大面积坏死,肝间质充满大量炎症细胞;脾脏淋巴细胞、网状内皮细胞严重坏死;肾间质充血,肾小管上皮细胞广泛坏死,肾小球毛细血管严重充血。[结论] 头背部体表皮肤溃烂,腹部及四肢出血,肝、脾、肾、胃肠道等多器官组织炎性病变是本病的示病症状。机体多器官组织严重病变是引起病蛙死亡的主要因素。

关键词: 牛蛙, 腐皮病, 红腿病, 组织病理学

Abstract: [Objective] To observe the pathological changes of sick Rana catesbeiana.[Method] The pathological changes in Rana catesbeiana with natural rotten-skin and red-leg disease were observed by light microscope after using paraffin section and H·E staining.[Results] Gross lesions included some parts of the skin mostly on head and back were rotten;erythema was seen on abdomen and leg skin;the liver,spleen and kidney were swollen with severe hemorrhage;gastrointestinal tract was inflamed with yellowish mucus.The main histopathological characterization of sick frog was parenchymal cell necrosis,hemorrhage,inflammatory cell infiltration were existed in main organ,including skin and muscle,liver,spleen,kidney and gastrointestinal.Catarrhal-hemorrhagic inflammation was observed in gastrointestinal tract.The epithelial cells of stomach were necrosis and falling off.The hepatocytes swelled with severely vacuolar degeneration,focal necrosis with inflammatory cell infiltration appeared.The lymphocyte and reticuloendothelial cell were severe necrosis.Degeneration and necrosis were appeared in renal tubular epithelia.The renal interstitium and renal glomerulus were hyperemia severely.[Conclusion] The typical symptom of the disease included rotten skin of head and back,haemorrhage of belly and leg skin,inflammatory lesion of hepar,spleen,kindey,and gastrointestinal tract.The serious lesion of several organs is the cause of death of sick frog.

Key words: Rana catesbeiana, rotten-skin disease, red-leg disease, histopathology

中图分类号: 

  • S947.2