四川农业大学学报 ›› 2016, Vol. 34 ›› Issue (02): 190-193.doi: 10.16036/j.issn.1000-2650.2016.02.011

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忍冬(Lonicera japonic Thunb.)果实中的环烯醚萜苷类成分

李静1, 潘少斌1, 王集会2, 张永清1, 宋林1   

  1. 1. 山东中医药大学药学院, 济南 250355;
    2. 山东中医药大学教学实验中心, 济南 250355
  • 收稿日期:2016-04-06 出版日期:2016-06-30 发布日期:2017-02-15
  • 作者简介:李静,博士研究生,讲师,从事中药质量控制与资源研究,E-mail:ljsdnu@163.com。
  • 基金资助:
    国家"十二五"科技支撑计划项目(2011BAI06B01);山东省自主创新专项项目(2013CXC20401)

Iridoid Glycosides from the Fruits of Lonicera japonica Thunb.

LI Jing1, PAN Shao-bin1, WANG Ji-hui2, ZHANG Yong-qing1, SONG Lin1   

  1. 1. College of Pharmacy, Shandong University of Traditional Chinese Medicine;
    2. Teaching Experience Center, Shandong University of Traditional Chinese Medicine, Jinan 250355, China
  • Received:2016-04-06 Online:2016-06-30 Published:2017-02-15

摘要: [目的] 在前期研究的基础上,进一步研究忍冬Lonicera japonica Thunb.果实的化学成分。[方法] 采用硅胶柱色谱、Sephadex LH-20等方法对忍冬果实乙醇提取物的乙酸乙酯部分进行分离纯化,并通过波谱技术和参考文献鉴定其结构。[结果] 分离得到了6种环烯醚萜苷类成分,分别鉴定为金吉苷、马钱素、马钱素-7-酮、獐牙菜苷、Demethylsecologanol、裂环氧化马钱素。[结论] 化合物1~6为首次从忍冬果实中分离得到。

关键词: 忍冬果实, 环烯醚萜苷, 化学成分

Abstract: [Objective] The aim of the study was to further investigate the chemical components from fruits of Lonicera japonica Thunb. based on prior studies. [Method] The chemical components of ethyl acetate fraction in fruits of L. japonica. were isolated and purified by silica column chromatography and sephadex LH-20. The structures were iden tified according to spectral analysis and references. [Results] Six iridoid glycosides were obtained and identified as Kingiside, Loganin, Ketologanin, Swerosid, Demethylsecologanol and Secoxyloganin. [Conclusion] For the first time, 1-6 compounds were obtained from fruits of L. japonica.

Key words: fruits of Lonicera japonica Thunb., iridoid glycosides, chemical constituents

中图分类号: 

  • R284.1