四川农业大学学报 ›› 0, Vol. ›› Issue (): 119-125.doi: 10.16036/j.issn.1000-2650.1984.02.003

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绵羊痒病在国内的首次报告

冯泽光1, 汪开毓1, 张鸿均2, 罗若兰2, 李茂3, 敖先成3, 田楠3   

  1. 1. 四川农学院畜牧兽医系;
    2. 四川省畜牧局兽医总站;
    3. 四川凉山彝族自治州畜牧局
  • 收稿日期:1984-09-11 出版日期:1984-06-30

REPORT OF SCRAPIE IN SHEEP IN CHINA

Feng Zeguang1, Wang Kaiyu1, Zhang Hongjun2, Luo Ruolan2, Li Mao3, Ao Xiancheng3, Tian Nan3   

  1. Sichuan Agricultural College, Ya'an, Sichuan, China
  • Received:1984-09-11 Online:1984-06-30

摘要: 1982年7月四川省凉山彝族自治州从苏格兰购回2岁左右的边区莱塔特(简称边莱)种羊115只。1983年4~5月和12月,先后发现其中有2只母羊和3只一岁龄的纯种后代羔羊出现明显的搔痒与神经症状,经检查未见螨和虱等外寄生虫。一只母羊因迅速失重,后躯瘫痪,躺卧不起,于濒死期剖杀。尸体剖检无明显病变。病理组织学切片观察,在中枢神经系统的脑干(延髓、脑桥、丘脑和纹状体)呈两侧对称性的损害,出现特征的空泡性神经元(所谓"气球样细胞")、灰质不同程度的海绵状变性和星形胶质细胞的肥大与增生等病变。#br#取脑和脾作细菌培养为阴性,以病羊脑悬浮液接种家兔未发病。#br#诊断是以呈现典型的痒病症状和脑内的组织损害为依据。

Abstract: This paper report the cccurrence of scrapie in 115 Border Leicester 2-year-old sheep imported from Scotland. From April to May and in December of 1983, two ewes and three purebred filial sheep showed pruritus and nervous signs. No mites and lice were found in itching areas. One of the two affected ewes lost weight rapidly, and locomotor incoordination and paralysis of the hind quarters were observed. It finally became recumbent and unable to rise. It was killed atthe agonal stage. There were no apparent gross lesions in necropsy. Microscopical examination showed characteristic vacuolated neurones (so-called "bubble cells"), spongy rarefaction of the grey matter and hypertrophy and proliferation of astrocytes found in brain stem(medulla, pons, Thalamus and corpus striatum) of the central nervous system. The lesions were bilaterally symmetrical. The diagnosis was based upon the clinical signs and characteristic pathohistologlcal lesions of central nervous system.

Key words: SCRAPIE, SHEEP, DIAGNOSIS